R. J. Hankinson traces the history of ancient Greek thinking about causation and explanation, from its earliest beginnings around 600 BC through to the middle of the first millennium of the Christian era. The ancient Greeks were the first Western civilization to subject the ideas of cause and explanation to rigorous and detailed analysis, and to attempt to construct theories about them on the basis of logic and experience. Hankinson examines the ways in which they dealt with questions about how and why things happen as and when they do, about the basic constitution and structure of things, about function and purpose, laws of nature, chance, coincidence, and responsibility. Such diverse questions are unified by the fact that they are all demands for an account of the world that will render it amenable to prediction and control; they are therefore at the root of both philosophical and scientific enquiry. Hankinson draws on a wide range of original sources, in philosophy, natural sciences, medicine, history, and the law, in order to create a synoptic picture of the growth and development of these central concepts in the Graeco-Roman world.